Loratadine rapidly-disintegrating tablets mean AUC and Cmax were 11% and 6% greater than that of the loratadine tablet values, respectively. Descarboethoxyloratadine bioequivalence was demonstrated between the two formulations. After 10 days of dosing, mean peak plasma concentrations were attained at 1.3 hours and 2.3 hours for parent and metabolite, respectively.
This medication is an antihistamine that treats symptoms such as itching, runny nose, watery eyes, and sneezing from "hay fever" and other allergies. A severe allergic reaction, known as anaphylaxis, is a rare, life-threatening emergency in which your body’s response to the allergen is sudden and affects the whole body. Anaphylaxis may begin with severe itching of your eyes or face.Continue Reading